What is the name of this movie?

The story: A man and his doctor wife go to his birthplace because he is dying of a genetic disorder and he needs to learn more about his life so she can save him. He was adopted and has spent his life looking for his family. He's also got one blue eye and one green eye, pretty creepy by itself. Well, they get to this small fishing village (I think it was filmed in Canada?) and find out there are some crazy batshit things happening. Cue to suspense, drama and people dying. In the end we find out that the man is from a LONG line of inbreeders that originated with a woman who was so vain she only made love to her twin brother (gross) and they created this HUGE clan of genetic mutants and creepy beings. The man with the blue/green eyes finds this clan and falls in love with the matriarch who is omg so creepy looking. He basically leaves his entire life behind, including the super smart, super devoted wife to live with his "family" and continue the inbreeding trend